Tripohist

Generic name:triprolidine hydrochloride
Dosage form: oral liquid
Drug class:Antihistamines

Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Tripohist Description

Tripohist™ Liquid is an alcohol free, sugar free red syrup for oral administration having an apple odor and flavor.

Each teaspoonful (5 mL) contains:

INACTIVE INGREDIENTS

Sodium Benzoate, Citric Acid, Saccharin Sodium, Glycerin, Sorbitol Solution, Apple Flavor, FD&C Red No. 40 and Purified Water.

Triprolidine Hydrochloride is an antihistamine, chemically it is: Pyridine, 2-[1-(4-methyl-phenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride, monohydrate, (E)-. It's structure is as follows:

C19H22N2•HCl•H2O M.W. 332.87

Tripohist - Clinical Pharmacology

Triprolidine provides symptomatic relief of conditions believed to depend wholly or partly upon the release of histamine. Triprolidine hydrochloride antagonizes the effects of histamine by competing for histamine-1 (H1) receptor sites. The serum half-life for triprolidine is 3 to 3.3 hours.

Indications and Usage for Tripohist

Triprolidine provides symptomatic relief of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, and mild uncomplicated allergic skin manifestations of urticaria...