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Trodelvy
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Trodelvy

Generic name:sacituzumab govitecan-hziy
Dosage form:   lyophilized powder for injection, for intravenous use
Drug class:Miscellaneous antineoplastics

Medically reviewed by Judith Stewart, BPharm. Last updated on Oct 12, 2021.

What is Trodelvy?

Trodelvy is a prescription medicine used to treat adults with:

  • a type of breast cancer that is estrogen and progesterone hormone receptor (HR) negative, and human epidermal growth factor receptor 2 (HER2) negative (also called triple-negative breast cancer). Trodelvy may be used:
    • when your breast cancer has spread to other parts of the body (metastatic) or cannot be removed by surgery, and
    • if you previously received two or more prior treatments, including at least one treatment for metastatic disease.
  • bladder cancer and cancers of the urinary tract that have spread or cannot be removed by surgery. Trodelvy may be used if you have:
    • received a platinum-containing chemotherapy medicine and
    • also received an immunotherapy medicine.

It is not known if Trodelvy is safe and effective in people with moderate or severe liver problems.

It is not known if Trodelvy is safe and effective in children.

Warnings

Trodelvy can cause serious side effects, including:

  • Low white blood cell count (neutropenia). Low white blood cell counts are common with Trodelvy and can sometimes be severe and lead to infections that can be life-threatening. Your healthcare provider should check your blood cell counts during treatment. If your white blood cell count is too low, your healthcare provider may need to lower your dose, give you a medicine to help prevent low blood cell count with future doses, or in some cases may stop treatment. Your healthcare provider may need to give you antibiotic medicines if you develop fever while your white blood cell count is low. Call your healthcare provider right away if you develop any of the f.