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Trulance
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Trulance

Generic name:plecanatideple-KAN-a-tide ]
Drug class:Guanylate cyclase-C agonists

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jan 7, 2021.

What is Trulance?

Trulance is used to treat chronic idiopathic constipation or irritable bowel syndrome with constipation.

Trulance works by activating certain substances within your intestines that help increase fluid secretion and muscle movement.

Trulance also causes changes in the consistency of your stools.

Warnings

You should not use Trulance if you are allergic to plecanatide, or if you have a blockage in your intestines.

Adults who cannot swallow Trulance tablets whole may crush the tablet and mix with applesauce or dissolve the tablet in water before swallowing. Trulance tablets may also be taken with water by adults through a nasogastric or gastric feeding tube.

Before taking this medicine

You should not use Trulance if you are allergic to plecanatide , or if you have:

  • a blockage in your intestines.

Do not give this medicine to a child younger than 6 years old.

Avoid using Trulance in anyone younger than 18 years old. In animal studies, plecanatide caused severe dehydration leading to death.

Tell your doctor if you are pregnant or breastfeeding.

How should I take Trulance?

Take Trulance exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

You may take Trulance with or without food. Swallow the tablet whole.

If you cannot swallow the tablet whole, you may crush and mix the...