Truxima

Generic name:rituximab [ ri-TUX-i-mab ]
Drug class:CD20 monoclonal antibodies

Medically reviewed by Philip Thornton, DipPharm. Last updated on Apr 1, 2021.

What is Truxima?

Truxima injection is a prescription medicine used alone or in combination with other medicines to treat the following conditions in adults:

• non-Hodgkin's lymphoma or chronic lymphocytic leukemia;

• adults with rheumatoid arthritis; or

• adults with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA).

Truxima is not to be used in the treatment of children.

Warnings

Truxima may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.

Tell your doctor if you have ever had hepatitis B. Truxima can cause this condition to come back or get worse.

Severe skin problems can also occur during treatment with Truxima. Call your doctor if you have painful skin or mouth sores, or a severe skin rash with blistering, peeling, or pus.

Some side effects may occur during the injection or within 24 hours afterward. Tell your caregiver right away if you feel itchy, dizzy, weak, light-headed, short of breath, or if you have chest pain, wheezing, sudden cough, or pounding heartbeats or fluttering in your chest.

Before taking this medicine

Truxima may cause a serious brain infection that can lead to disability or death. This infection may be more likely if have used an immunosuppressant drug in the past, or if you have...