Twynsta
Generic name:amlodipine and telmisartan [ am-LOE-de-peen-and-TEL-me-SAR-tan ]
Drug class:Angiotensin II inhibitors with calcium channel blockers
What is Twynsta?
Twynsta contains a combination of amlodipine and telmisartan. Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow.
Telmisartan is an angiotensin II receptor antagonist. Telmisartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Twynsta is used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.
Warnings
Do not use Twynsta if you are pregnant. It could harm the unborn baby. Use effective birth control. Stop using Twynsta and tell your doctor right away if you become pregnant.
You should not use Twynsta if you are allergic to amlodipine (Norvasc) or telmisartan (Micardis), or if you have diabetes and are taking aliskiren.
Before you use Twynsta, tell your doctor about all your medical conditions and allergies. Also make sure your doctor knows if you are pregnant or breast-feeding. In some cases, you may not be able to use Twynsta, or you may need a dose adjustment or special precautions.
Certain other drugs may interact with amlodipine and telmisartan or should not be used at the same time. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.
In rare cases, Twynsta can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Before taking this medicine
You should not use this medicine if you are allergic to amlodipine (Norvasc) or telmisartan (Micardis).
If you have diabetes, do not use Twynsta together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).
You may also need to avoid taking Twynsta with aliskiren if you have kidney disease.
To make sure Twynsta is safe for you, tell your doctor if you have:
kidney disease (or if you are on dialysis);
liver disease;
heart disease;
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or
if you are on a low-salt diet.
Do not use Twynsta if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Twynsta can cause injury or death to the unborn b...
