Tybost
Generic name:cobicistat [ koe-BIK-i-stat ]
Drug class:Antiviral boosters
What is Tybost?
Tybost reduces the action of enzymes in your liver that break down certain antiviral medicines. This allows the antiviral medicines to be used more safely and effectively at lower doses.
Tybost is given together with atazanavir (Reyataz) or darunavir (Prezista) to treat human immunodeficiency virus (HIV), the virus that can cause acquired immunodeficiency syndrome (AIDS).
Tybost is used to increase your blood levels of these medicines, helping to make them safer and more effective at lower doses.
When given with atazanavir, Tybost is for use in adults and children weighing at least 77 pounds (35 kilograms). When given with darunavir, Tybost is for use in adults and children weighing at least 88 pounds (40 kilograms).
Tybost is not an antiviral medicine and will not treat HIV or AIDS. It is given only to help increase your blood levels of atazanavir or darunavir.
Warnings
Tybost is not a complete treatment and must be used in combination with other antiviral medicines your doctor has prescribed. However, there are certain antiviral medicines that should not be taken in combination with cobicistat. Follow your doctor's medication and dosing instructions very carefully.
Tybost is recommended for use only with atazanavir or darunavir. You should not take this medicine with other protease inhibitor HIV medicines, such as fosamprenavir, nelfinavir, saquinavir, or tipranavir.
You should not take cobicistat with darunavir if you are taking darunavir twice daily. You should not take cobicistat with atazanavir if you also take indinavir, irinotecan, or nevirapine.
Many drugs can interact with cobicistat and some should not be used at the same time. Tell your doctor about all your current medicines and any you start or stop using.
Before taking this medicine
Tybost is not a complete treatment and must be used in combination only with atazanavir or darunavir. You should not take this medicine with any other antiviral medicines that your doctor has not prescribed.
You should not take Tybost if you are allergic to cobicistat.
Many drugs can interact and cause dangerous effects that could lead to death. Some drugs should not be used together.
You should not take cobicistat with atazanavir if you also take:
indinavir;
nevirapine; or
birth control pills that contain drospirenone and ethinyl estradiol (Beyaz, Sayfral, Yasmin, Yaz).
You should not take Tybost with atazanavir or darunavir if you also take:
