Uplizna

Generic name:inebilizumab-cdon (injection, for intravenous use)
Drug class:Selective immunosuppressants

Medically reviewed by Judith Stewart, BPharm. Last updated on Jun 25, 2020.

Warnings

Uplizna may cause serious side effects, including:
Infusion reactions. Uplizna can cause infusion reactions that can be serious or may cause you to be hospitalized. You will be monitored during your infusion and for at least 1 hour after each infusion of Uplizna for signs and symptoms of an infusion reaction. Tell your healthcare provider right away if you get any of these symptoms:

• headache
• nausea
• sleepiness
• shortness of breath
• fever
• muscle aches
• rash

If you develop an infusion reaction, your healthcare provider may need to stop or slow down the rate of your infusion and treat your symptoms.
Infections. Infections can happen during treatment with Uplizna. Tell your healthcare provider right away if you have an infection or get any of these symptoms:

• • painful and frequent urination
  • nasal congestion, runny nose, sore throat, fever, chills, cough, body aches
• Uplizna taken before or after other medicines that weaken the immune system may increase your risk of getting infections.
• Hepatitis B virus (HBV) reactivation. Before starting treatment with Uplizna, your healthcare provider will do blood tests to check for hepatitis B viral infection. If you have ever had hepatitis B virus infection, the hepatitis B virus may become active again during or after treatment with Uplizna. Hepatitis B virus becoming active again (called reactivation) may cause serious liver problems, including liver failure or death. Your healthcare provider will monitor you if you are at risk for hepatitis B virus reactivation during treatment and after you stop receiving Uplizna.
• Progressive Multifocal Leukoencephalopathy (PML). PML may happen with Uplizna. PML is a rare...