Dosage form: ointment
Drug class:Topical emollients
Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.
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DESCRIPTION:
Kylemore 50% Urea Ointment is a keratolytic emollient, which is a gentle, yet potent, tissue softener for skin. Each gram of Kylemore 50% Urea Ointment contains 50% Urea, Caprylic/Capric Triglyceride, Carbomer, Cetyl Alcohol, Edetate Disodium, Glycerin, Hydroxyethylcellulose, Lactic Acid, Linoleic Acid, PEG-6, Polysorbate 60, Propylene Glycol, Purified Water, Sorbitan Stearate, Tocopherol (Vitamin E), Triethanolamine, Xanthan Gum, and Zinc Pyrithione.
Urea is a diamide of carbonic acid with the following chemical structure:
CLINICAL PHARMACOLOGY:
Urea gently dissolves the intercellular matrix, which results in loosening the horny layer of skin and shedding scaly skin at regular intervals, thereby softening hyperkeratotic areas. Urea also hydrates and gently dissolves the intercellular matrix of the nail plate, which can result in the softening and eventual debridement of the nail plate.