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Urea Solution
  • Professionals
  • FDA PI

Urea Solution

Dosage form: topical solution
Drug class:Topical emollients

Medically reviewed by Drugs.com. Last updated on Mar 22, 2022.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

For external use only. Not for ophthalmic use.

Rx Only

Description: Urea 40% Nail Film is a keratolytic, emollient which is a gentle, yet potent, tissue softener for nails and skin.

Each gram of Urea 40% Nail Film suspension with applicator contains 40% urea, sodium hyaluronate disodium EDTA, glycerin, hydroxyethyl cellulose, PEG-6 caprylic/capric glycerides, purified water and xanthan gum.

Urea is a diamide of carbonic acid with the following chemical structure:

Clinical Pharmacology: Urea gently dissolves the intercellular matrix which results in loosening the horny layer of skin and shedding scaly skin at regular intervals, thereby softening hyperkeratotic areas. Urea also hydrates and gently dissolves the intercellular matrix of the nail plate which can result in the softening and e...