Dosage form: topical suspension
Drug class:Topical emollients
Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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DESCRIPTION:
Each gram of 50% Urea Topical Suspension contains: Urea 50%, Caprylic/Capric Triglyceride, Carbomer, Cetyl Alcohol, Disodium EDTA, Glycerin, Hydroxyethylcellulose, Lactic Acid, Linoleic Acid, PEG-6, Polysorbate 60, Propylene Glycol, Water, Salicylic Acid, Sorbitan Stearate, Titanium Dioxide, Triethanolamine, Tocopheryl Acetate, Xanthan Gum.
Urea is a diamide of carbonic acid with the following chemical structure:
NH2
|
C=O
|
NH2
CLINICAL PHARMACOLOGY:
Urea gently dissolves the intercellular matrix, which results in loosening the horny layer of skin and shedding scaly skin at regular intervals, thereby softening hyperkeratotic areas.
PHARMACOKINETICS:
The mechanism of action of topically applied Urea is not yet known.
INDICATIONS AND USES:
For debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous o
