Urealac
Generic name:urea lotion
Dosage form: lotion
Drug class:Topical emollients
Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
On This Page
For external use only. Not for ophthalmic use.
The Urealac brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Urealac Description
Urealac (35% Urea) LOTION is a keratolytic emollient, which is a gentle, yet potent, tissue softener for skin. Each gram of Urealac lotion contains: 35% Urea, Carbomer, Cetyl Alcohol, Edetate Disodium, Hydroxyethyl Cellulose, Lactic Acid, Mineral Oil, Polysorbate 80, Purified Water, Sorbitan Stearate, Trolamine, Vitamin E, Xanthan Gum, Zinc Pyrion.
Urea is a diamide of carbonic acid with the following chemical structure:
Urealac - Clinical Pharmacology
Urea gently dissolves the intercellular matrix, which results in loosening the horny layer of skin and shedding scaly skin at regular intervals, thereby softening hyperkeratotic areas.
PHARMACOKINETICS
The mechanism of action of topically applied Urea is not yet known.
Indications and Usage for Urealac
For debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous or prurient debris or eschar. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis, keratoderma, corns and calluses.
