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Urofollitropin
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Urofollitropin

Generic name: urofollitropin [ URE-oh-FOL-i-TROE-pin ]
Brand names: Bravelle, Metrodin, Fertinex
Dosage form: injectable powder for injection (75 intl units)
Drug class:Gonadotropins

Medically reviewed by Drugs.com on Oct 26, 2021. Written by Cerner Multum.

What is urofollitropin?

Urofollitropin is a purified form of a hormone called follicle-stimulating hormone (FSH). This hormone is important in the development of follicles (eggs) that are produced by the ovaries in women.

Urofollitropin is used together with other medicines to treat infertility in women with FSH deficiency. Urofollitropin is also used to help the ovaries produce multiple eggs for use in "in-vitro" fertilization.

Urofollitropin alone will not cause ovulation (production of an egg by the ovaries). You will need to receive other medicines to stimulate ovulation.

Urofollitropin may also be used for purposes not listed in this medication guide.

Warnings

You should not use urofollitropin if you have primary ovarian failure, abnormal vaginal bleeding, uncontrolled thyroid or adrenal gland disorders, an ovarian cyst, breast cancer, uterine or ovarian cancer, a pituitary gland tumor, or infertility that is not caused by lack of ovulation.

Do not use urofollitropin if you are pregnant.

Stop using urofollitropin, do not have sexual intercourse, and call your doctor right away if you have any of the following symptoms: stomach pain, bloating, nausea, vomiting, diarrhea, rapid weight gain, little or no urinating, or pain when you breathe, rapid heart rate, or shortness of breath.

Before taking this medicine

You should not use this medicine if you are allergic to urofollitropin or similar medicines (such as follitropin, lutropin alfa, menotropin), or if you have:

  • a condition called primary ovarian failure;

  • cancer of the breast, uterus, or ovary;

  • an untreated or uncontrolled disorder of your thyroid or adrenal gland;

  • infertility that is not caused by lack of ovulation;

  • abnormal vaginal bleeding that has not been checked by a doctor;

  • an ovarian cyst;

  • a tumor of your pituitary gland; or

  • if you are pregnant.

Your doctor will perform blood tests and a pelvic exam to make sure you do not have conditions that would prevent you from safely using urofollitropin.

Your male sexual partner's fertility should also be checked before you are treated with urofollitropin.

To make sure urofollitropin is safe for you, tell your doctor if you have: