Vaccinia immune globulin, human (Intravenous)
Medically reviewed by Drugs.com. Last updated on May 2, 2022.
Immune globulin intravenous (human) (IGIV) products have been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, proximal tubular nephropathy, and death. Use caution in patients predisposed to acute renal failure and administer at the minimum concentration available and the minimum rate of infusion practicable. Higher rates of renal failure were associated with IGIV products containing sucrose and administered at daily doses of 400 mg/kg or greater. Vaccinia immune globulin contains sucrose (5%) as a stabilizer, and the recommended dose is 100 mg/kg .
Commonly used brand name(s)
In the U.S.
- Vaccinia Immune Globulin, Human
Uses for vaccinia immune globulin, human
Vaccinia immune globulin is used to treat infections caused by the vaccinia virus.
Before using vaccinia immune globulin, human
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For vaccinia immune globulin, human, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to vaccinia immune globulin, human or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Studies on vaccinia immune globulin, human have been done only in adult patients, and there is no known specific information comparing use of vaccinia immune globulin in children with use in other age groups.
Geriatric
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of vaccinia immune globulin in the elderly with use in other age groups.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking vaccinia immune globulin, human, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using vaccinia immune globulin, human with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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