Vagifem Vaginal Inserts

Generic name:estradiol vaginal (ES tra DYE ole VA jin ul))
Drug classes:Estrogens, Miscellaneous vaginal agents

Medically reviewed by Philip Thornton, DipPharm. Last updated on Feb 10, 2022.

What is Vagifem?

Vagifem vaginal inserts contain estradiol, a form of estrogen. Estrogen is a female sex hormone that regulates many processes in the body.

Vagifem is used after menopause to treat menopause symptoms (such as dryness, burning, and irritation) in and around the vagina.

Vagifem is a small, white, round, film-coated, bi-convex vaginal insert containing 10 mcg of estradiol. Each vaginal insert is 6 mm in diameter and is administered in a disposable applicator.

Warnings

You should not use Vagifem if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, if you will have major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.

Do not use Vagifem if you are pregnant.

Estradiol may increase your risk of developing a condition that may lead to uterine cancer. Report any unusual vaginal bleeding right away.

Using Vagifem can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, or ovaries. Vagifem should not be used to prevent heart disease, stroke, or dementia.

Before taking this medicine

You should not use Vagifem if you are allergic to estradiol, or if you have:

• unusual vaginal bleeding that has not been checked by a doctor;

• liver disease;

• a history of heart attack, stroke, or blood clot...