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Venetoclax
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Venetoclax

Generic name: venetoclax [ ven-ET-oh-klax ]
Brand names: Venclexta, Venclexta Starting Pack
Dosage forms: oral kit (10 mg-50 mg-100 mg); oral tablet (10 mg; 100 mg; 50 mg)
Drug class:Miscellaneous antineoplastics

Medically reviewed by Drugs.com on Jun 4, 2021. Written by Cerner Multum.

What is venetoclax?

Venetoclax is used to treat chronic lymphocytic leukemia or small lymphocytic leukemia in adults.

Venetoclax is also used in combination with other medicines to treat acute myeloid leukemia in adults who are 75 years or older, or who cannot use standard chemotherapy due to other medical conditions.

Venetoclax may also be used for purposes not listed in this medication guide.

Warnings

Call your doctor at once if you have a fever, chills, joint or muscle pain, tiredness, confusion, shortness of breath, fast or slow heartbeats, nausea, vomiting, dark or cloudy urine, or a seizure (convulsions).

Drink 6 to 8 full glasses of water each day to help prevent these side effects.

Before taking this medicine

Some drugs should not be used with venetoclax. Your treatment plan may change if you also use:

  • an antibiotic or antifungal medicine;

  • heart medication; or

  • antiviral medicine to treat hepatitis C or HIV.

Do not start or stop using any medicine without asking your doctor.

Tell your doctor if you have ever had:

  • liver or kidney disease;

  • an electrolyte imbalance (such as low levels of potassium or calcium in your blood);

  • gout, or high levels of uric acid in your blood; or

  • if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use birth control while using venetoclax and for at least 30 days after your last dose. Tell your doctor if you become pregnant.

It may be harder for a man to get a woman pregnant while you using venetoclax.

You should not breastfeed while using this medicine and for at least 1 week after your last dose.

How should I take venetoclax?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medici...