Vexa Patch

Generic name: allantoin, lidocaine and petrolatum
Dosage form: patch

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Active Ingredients

Allantoin

Lidocaine

Petrolatum

Other Ingredients

Vitamin E, Onion Extract

Skin Protectant

Topical Anesthetic

Skin Protectant

Warnings

For external use only

Avoid contact with eyes

Stop use and ask a doctor if condition worsens, symptoms last more than 7 dasy or clear up and occure again within a few days

Do not use on deep puncture wounds, animal bites, serious burns

If pregnant or breast feeding, contact physician prior to use

Do not use in large quantities, particularly over raw sufaces or blistered areas

Uses

Scar management

Temporarily protects minor cuts, scrapes and burns

Temporarily relief of pain associated with minor cuts, scrapes and minor skin irritations

Directions

Clean and dry affected area

Remove mesh from backing and apply to affected area

Use only one mesh at a time, and maximum of four mesh/day

Leave mesh on affected area for up to 8 hours

Do not use mesh for longer than five consecutive days

Children under 12 should consult physician prior to use

Store below 25 degrees. Avoid direct sunlight.

DESCRIPTION:

Vexa (Allantoin 2%/Lidocaine 4%/Petrolatum 30%) is comprised of an adhesive material containing Allantoin 2%, Lidocaine 4% and petrolatum 30% which is applied to a woven polyester backing and covered with a PET film release line. The release liner is removed prior to application to the skin. The size of the patch is 12.5 cm x
8.5cm.

Allantoin is chemically designated as 1-(2,5-Dioxo-4-imidazolidinyl).
It is a white powder that is stable, incompatible with strong oxidizing agents. It has a melting point of 230°C. It has the following structure:

Lidocaine is chemically designated as 2-(diethylamino)-N-(2,6- dimethylphenyl), has an octanol: water partition ration of 43 at pH
7.4, and has the following structure:

Each adhesive patch contains 34 mg of Allantoin and 68 mg of Lidocaine in a petrolatum base. It also contains the following inactive ingredients: Vitamin E and Onion Extract.

CLINICAL PHARMACOLOGY: Pharmacodynamics

Allantoin works by slowing bacterial growth and loosing and softening scales and crust. The keratolytic effect and abrasive and astringent properties of Allantoin are used in skin softening cosmetic preparation.

Allantoin is a moisturizing, soothing, healing, anti-irritating, keratoyltic and non-toxic agent.