Vibegron
Generic name: vibegron
Brand name: Gemtesa
Dosage form: oral tablet
Drug class:Urinary antispasmodics
What is vibegron?
Vibegron is a type of drug called a beta-3 agonist. It is used to treat overactive bladder. Overactive bladder is a condition which causes a frequent and sudden urge to urinate that is hard to control.
Vibegron works by activating beta-3 adrenergic receptors in the bladder. This relaxes the main muscle in the bladder wall - the detrusor smooth muscle - while the bladder is filling. Relaxation of the detrusor smooth muscle allows you to hold more urine in your bladder, which helps to treat the symptoms of overactive bladder
Vibegron was approved by the US Food and Drug Administration (FDA) in December 2020 and launched under the brand name Gemtesa the following year.
What is vibegron used for?
Vibegron is a prescription medicine for adults that is used to treat the following symptoms of overactive bladder:
- urge urinary incontinence: a strong need to urinate with leaking or wetting accidents
- urgency: the need to urinate right away
- frequency: urinating often
It is not known if vibegron is safe and effective in children.
Who should not take vibegron?
Do not take vibegron if you are allergic to vibegron or any of the ingredients in this medication. See below for a complete list of ingredients.
What should I tell my doctor before taking vibegron?
Before you take vibegron, tell your doctor about all of your medical conditions, including if you:
- have liver problems.
- have kidney problems.
- have trouble emptying your bladder or you have a weak urine stream.
How should I take vibegron?
- Take vibegron exactly as your doctor tells you to take it.
- Take 1 vibegron tablet, by mouth, 1 time a day with or without food.
- Swallow vibegron tablets whole with a glass of water.
- You may also crush vibegron tablets, mix with 1 tablespoon (about 15 mL) of applesauce, and take right away with a glass of water.
Dosing information
The recommended dose of vibegron is one 75 mg tablet once daily.
See full prescribing information for more information about vibegron dosing.
What are the side effects of vibegron?
Vibegron may cause serious side effects including:
- inability to empty your bladder (urinary retention). Vibegron may increase your chances of not being ...
