Viberzi

Generic name:eluxadoline [ EL-ux-AD-oh-leen ]
Drug class:Peripheral opioid receptor mixed agonists / antagonists

Medically reviewed by Philip Thornton, DipPharm. Last updated on Aug 5, 2020.

What is Viberzi?

Viberzi works directly in your intestines to slow the movement of food during digestion. Eluxadoline also makes the nerves in your intestines less sensitive to stimulation.

Viberzi is used to treat irritable bowel syndrome when the main symptom is diarrhea.

Viberzi may also be used for purposes not listed in this medication guide.

Warnings

You should not use Viberzi if you have a pancreas disorder, severe liver disease, alcoholism, a blockage in your intestines, a gallbladder disorder, or if your gallbladder has been removed.

Viberzi may cause pancreatitis or constipation, which could be severe or lead to hospitalization. Call your doctor at once if you have severe or ongoing constipation, severe pain in your upper stomach spreading to your back (with or without nausea and vomiting).

Before taking this medicine

You should not use Viberzi if you are allergic to eluxadoline, or if you have:

• severe constipation or a blockage in your intestines;

• a history of gallbladder obstruction, or if your gallbladder has been removed;

• digestive problems caused by a muscle valve called the sphincter of Oddi (SFINK-ter of OD-dee);

• severe liver disease;

• a pancreas disorder; or

• a habit of drinking more than 3 alcoholic beverages per day.

To make sure Viberzi is safe for you, tell your doctor if you have ever had:

• liver disease; or

• kidney disease (or if yo...