Generic name:larotrectinib [ LAR-oh-TREK-ti-nib ]
Drug class:Multikinase inhibitors
What is Vitrakvi?
Vitrakvi is a prescription medicine used to treat certain tumors that are caused by an abnormal "NTRK" gene. Larotrectinib is used when the cancer has spread to other parts of the body or cannot be removed with surgery or other cancer treatments.
Vitrakvi is sometimes given after other cancer treatments did not work or have stopped working.
Vitrakvi was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.
Warnings
Your healthcare provider will perform a test to make sure that Vitrakvi is right for you.
It is not known if Vitrakvi is safe and effective in children younger than 1 month of age.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Certain other medicines may affect how larotrectinib works. Keep a list of all your medicines to show your healthcare provider and pharmacist.
Before taking this medicine
To make sure Vitrakvi is safe for you, tell your doctor if you have ever had:
liver disease; or
nerve problems.
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using this medicine should use effective birth control to prevent pregnancy. Larotrectinib can harm an unborn baby or cause birth defects if the mother or father is using this medicine. Keep using birth control for at least 1 week after your last dose.
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