Vivaglobin

Generic name:immune globulin (subcutaneous) [ im-MYOON-GLOB-yoo-lin ]
Drug class:Immune globulins

Medically reviewed by Philip Thornton, DipPharm. Last updated on Nov 24, 2021.

What is Vivaglobin?

Vivaglobin is a sterilized solution made from human plasma. It contains the antibodies to help your body protect itself against infection from various diseases.

Vivaglobin subcutaneous (for injection under the skin) is used to treat primary immunodeficiency (PI). This includes, but is not limited to, the primary immunodeficiency in common variable immunodeficiency (CVID), X-linked agammaglobulinemia, congenital agammaglobulinemia, Wiskott-Aldrich syndrome, and severe combined immunodeficiencies.

Vivaglobin may also be used for purposes not listed in this medication guide.

Warnings

You should not use Vivaglobin if you have a condition called hyperprolinemia (high level of a certain amino acid in the blood).

Vivaglobin can cause blood clots. A blood clot may be more likely if you have risk factors such as heart disease, blood circulation problems, estrogen use, a history of blood clots, if you are 65 years or older, if you have been bed-ridden, or if you are using a catheter.

Stop using Vivaglobin and call your doctor at once if you have:

• signs of a blood clot in the brain--sudden numbness or weakness (especially on one side of the body), slurred speech, problems with vision or balance;

• signs of a blood clot in the heart or lung--chest pain, rapid heart rate, sudden cough, wheezing, rapid breathing, coughing up blood; or

• signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs.

Vivaglobin can also harm your kidneys, especially if you already have kidney disease or if you also use certain other medicines. Many other drugs (including some over-the-counter medicines) can be harmful to the kidneys.

Call your doctor at once if you have signs of a kidney problem, such as swelling, rapid weight gain, and little or no urinating.

Drink plenty of liquids while you are using Vivaglobin to help improve your blood flow and keep your kidneys working properly.

Before using Vivaglobin

You should not use Vivaglobin if you have ever had an allergic reaction to an immune globulin, or if you have:

• immune globulin A (IgA) deficiency with antibody to IgA; or

• a condition called hyperprolinemia (high level of a certain amino acid in the blood).

Immune globulin can harm your kidneys or cause blood clots. To make sure Vivaglobin is safe for you, tell your doctor if you have:

• heart disease, blood circulation problems or a blood vessel disorder;

• a history of stroke or blood clot;