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Bacitracin (EENT)
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  • AHFS Monographs

Bacitracin (EENT)

Class: Antibacterials
VA Class: DE101
CAS Number: 1405-87-4


Bacitracin, Bacitracin Zinc (EENT) is also contained as an ingredient in the following combinations:
Bacitracin Zinc and Polymyxin B Sulfate
Neomycin and Polymyxin B Sulfates and Bacitracin Zinc
Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone
Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone Acetate

Medically reviewed by Drugs.com on May 4, 2022. Written by ASHP.

Introduction

Antibacterial; polypeptide antibiotic.

Uses for Bacitracin (EENT)

Bacterial Ophthalmic Infections

Topical treatment of superficial infections of the eye involving the conjunctiva and/or cornea caused by susceptible bacteria.

Used in fixed combination with polymyxin B with or without neomycin for topical treatment of superficial infections of the eye involving the conjunctiva and/or cornea (e.g., conjunctivitis, keratitis, keratoconjunctivitis, blepharitis, blepharoconjunctivitis) caused by susceptible bacteria.

Mild, acute bacterial conjunctivitis often resolves spontaneously without anti-infective treatment. Although topical ophthalmic anti-infectives may shorten time to resolution and reduce severity and risk of complications, avoid indiscriminate use of topical anti-infectives. Treatment of acute bacterial conjunctivitis generally is empiric; use of a broad-spectrum topical ophthalmic antibacterial usually recommended. In vitro staining and/or cultures of conjunctival material may be indicated in management of recurrent, severe, or chronic purulent conjunctivitis or when acute conjunctivitis does not respond to initial empiric topical treatment.

Because bacterial keratitis may be associated with subsequent loss of vision as the result of corneal scarring or topographic irregularities and because untreated or severe bacterial keratitis may result in corneal perforation with potential for endophthalmitis and possible loss of the eye, optimal management involves rapid evaluation and diagnosis, tim