Vivjoa

Generic name: oteseconazole
Dosage form: capsules
Drug class:Azole antifungals

Medically reviewed by Judith Stewart, BPharm. Last updated on May 11, 2022.

What is Vivjoa?

• Vivjoa is a prescription antifungal medicine used to reduce the risk of vaginal yeast infections that keep coming back (recurrent vulvovaginal candidiasis, RVVC) in females with a history of RVVC.
• Vivjoa should only be taken by females who are not pregnant and who are NOT able to become pregnant.

It is not known if this medicine is safe and effective in females who have not had their first menstrual period.

Who should not take Vivjoa?

You should not take Vivjoa if you:

• Are able to become pregnant.
• Are pregnant or plan to become pregnant. Vivjoa may harm your unborn baby. Tell your doctor if you are pregnant, think you might be pregnant, or plan to become pregnant.
• Are breastfeeding or plan to breastfeed. It is not known if Vivjoa passes into your breastmilk.
• Are allergic to oteseconazole or any of the ingredients. See the end of this page for a complete list of ingredients.

Before taking Vivjoa

Before you start treatment, tell your doctor about all of your medical conditions, including if you:

• have kidney problems
• have liver problems

What other drugs will affect Vivjoa?

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your doctor if you take medicines called breast cancer resistance protein (BCRP) transporter substrates, including:

• rosuvastatin
• prazosin
• glyburide
• cimetidine
• sulfasalazine
• zidovudine
• lamivudine.

Ask your doctor or pharmacist if you are not sure. Taking Vivjoa (a BCRP inhibitor) with BCRP transporter substrates may increase the risk of side effects with these medicines.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

How should I take Vivjoa?

There are two recommended Vivjoa dosage regimens: one with Vivjoa only, and the other with Vivjoa and fluconazole. Your doctor will advise the best dosage regimen for you.

For the Vivjoa-only Dosage Regimen:

• Take Vivjoa exactly as your doctor tells you to take it. Talk to your doctor if you have any questions.
  • On Day 1: Take 600 mg (four capsules as a single dose), by mouth then,
  • On Day 2: Take 450 mg (three capsules as a single dose), by mouth the..