Von Willebrand factor (recombinant)
Generic name: von Willebrand factor (recombinant) [ von-WIL-e-brand-FAK-tor ]
Brand names: Vonvendi, Wilfactin
Dosage form: intravenous powder for injection (recombinant)
Drug class:Miscellaneous coagulation modifiers
What is von Willebrand factor?
Von Willebrand factor is a naturally occurring protein in the blood that helps blood to clot. People with an inherited blood-clotting disorder called von Willebrand disease do not have enough of this protein in their blood. A lack of von Willebrand factor can cause uncontrolled bleeding.
Von Willebrand factor is used to control bleeding episodes in adults with von Willebrand disease.
Von Willebrand factor may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use von Willebrand factor if you have ever had a severe allergic reaction to von Willebrand factor, or if you are allergic to mice or hamsters.
To make sure von Willebrand factor is safe for you, tell your doctor if you have ever been told that you have:
inhibitors to von Willebrand factor; or
inhibitors to blood coagulation factor VIII.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether von Willebrand factor passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.
How is von Willebrand factor given?
Von Willebrand factor is injected into a vein through an IV. You may be shown how to use an IV at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Von Willebrand factor is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine. Mixed medicine must be used within 3 hours if you keep it at room temperature.
Do not shake the mixed medicine. Prepare your dose only when you are ready to give an injection.
Do not use the medicine if it looks cloudy or has particles in it. Call your pharmacist for new medicine.
Tell your doctor if you have any changes in weight. Von Willebrand factor do...
