Vonvendi
Generic name:von Willebrand factor (recombinant) [ von-WIL-e-brand-FAK-tor ]
Drug class:Miscellaneous coagulation modifiers
What is Vonvendi?
Vonvendi is a naturally occurring protein in the blood that helps blood to clot. People with an inherited blood-clotting disorder called von Willebrand disease do not have enough of this protein in their blood. A lack of von Willebrand factor can cause uncontrolled bleeding.
Vonvendi is used in adults (age 18 years and older) diagnosed with von Willebrand disease to:
treat and control bleeding episodes
prevent excessive bleeding during and after surgery
- reduce the number of bleeding episodes when used regularly (prophylaxis);
Vonvendi may also be used for purposes not listed in this medication guide.
Warnings
You should not use Vonvendi if you:
are allergic to any ingredients in Vonvendi; or.
are allergic to mice or hamsters.
Tell your healthcare provider if you are pregnant or breastfeeding because Vonvendi may not be right for you.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use Vonvendi if you have ever had a severe allergic reaction to this medicine, or if you are allergic to mice or hamsters.
To make sure Vonvendi is safe for you, tell your doctor if you have ever been told that you have:
inhibitors to von Willebrand factor; or
inhibitors to blood coagulation factor VIII.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether von Willebrand factor passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.
How is Vonvendi given?
Vonvendi is injected into a vein through an IV. You may be shown how to use an IV at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Vonvendi is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine. Mixed medicine must be used within 3 hours if you keep it at room temperature.
Do not shake the mixed medicine. Prepare your dose only when you are ready to give an injection.
Do not use the medicine if it looks cloudy or has particles in it. Call your pharmacist for new medicine.
Tell your doctor if you have any chan...
