Voretigene neparvovec ophthalmic
Generic name: voretigene neparvovec ophthalmic [ voe-RET-i-jeen-ne-PAR-voe-vek-off-THAL-mik ]
Brand name: Luxturna
Dosage form: intraocular suspension (-)
Drug class:Miscellaneous ophthalmic agents
What is voretigene neparvovec ophthalmic?
Voretigene neparvovec ophthalmic (for use in the eyes) is used to treat diseases of the retina that can cause night blindness, light sensitivity, and progressive vision loss.
Voretigene neparvovec ophthalmic is for use only in people with a specific gene mutation. Before you receive voretigene neparvovec ophthalmic, you will need a medical test to make sure you have this gene mutation.
Your doctor will also determine whether you have enough remaining cells in your retina to be safely treated with this medicine.
Voretigene neparvovec ophthalmic may also be used for purposes not listed in this medication guide.
Warnings
Voretigene neparvovec can cause changes in your retina that could lead to vision loss. Talk to your doctor about the risks and benefits of this medicine.
Before taking this medicine
Voretigene neparvovec is not approved for use by anyone younger than 12 months or older than 65 years.
Tell your doctor if you are pregnant or breast-feeding.
How is voretigene neparvovec ophthalmic given?
Voretigene neparvovec ophthalmic is given as a one-time injection into each eye. You will receive this injection in your doctor's office or other clinic setting.
You may be given a steroid medication to take by mouth, starting 3 days before your injection. Keep using the steroid for as long as your doctor has prescribed.
Voretigene neparvovec is usually given into each eye at separate times, at least 6 days apart.
Your doctor will use a medicine to numb your eye before giving you the voretigene neparvovec injection.
For at least 24 hours after each injection, you will need to rest lying down as much as possible.
Your eyes will be checked periodically to make sure the medicine has been effective and has not caused serious side effects.
You should not stop using the steroid medication suddenly. Follow your doctor's instructions about tapering your dose.
Small amounts of voretigene neparvovec ophthalmic will remain in your tears for a short period of time. For at least 7 days after each injection: place all used bandages, eye dressings, or used tissues into sealed bags and throw them away in the trash.
