Voretigene neparvovec-rzyl (Injection)

Medically reviewed by Drugs.com. Last updated on Dec 19, 2021.

Uses for voretigene neparvovec-rzyl

Voretigene neparvovec-rzyl injection is used to treat retinal dystrophy (a rare form of inherited loss of vision) with confirmed biallelic RPE65 mutation.

Voretigene neparvovec-rzyl must be given only by or under the direct supervision of your doctor.

Before using voretigene neparvovec-rzyl

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For voretigene neparvovec-rzyl, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to voretigene neparvovec-rzyl or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of voretigene neparvovec-rzyl injection in children 12 months of age and older. Use is not recommended in children younger than 12 months of age.

Geriatric

Appropriate studies have not been performed on the relationship of age to the effects of geriatric-specific problems that would limit the usefulness of voretigene neparvovec-rzylin injection in the elderly. Safety and efficacy have not been established.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper use of voretigene neparvovec-rzyl

Your doctor will give you voretigene neparvovec-rzyl through a needle into your retina (part of the eye). It is to be injected into each eye separately at least 6 days apart.

You may be given an oral steroid medicine before, during, and after treatment with voretigene neparvovec-rzyl in the first eye and to be repeated with treatment of your other eye.

Your doctor may want you to lie down as much as possible for 24 hours after treatment.