Vorinostat

Generic name: vorinostat [ vor-IN-o-stat ]
Brand name: Zolinza
Dosage form: oral capsule (100 mg)
Drug class:Histone deacetylase inhibitors

Medically reviewed by Drugs.com on Dec 20, 2021. Written by Cerner Multum.

What is vorinostat?

Vorinostat is used to treat skin problems caused by cutaneous T-cell lymphoma.

Vorinostat is usually given after other treatments did not work or have stopped working.

Vorinostat may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Tell your doctor if you have ever had:

• diabetes or high blood sugar;

• a blood clot;

• liver disease;

• an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or

• any allergies.

Vorinostat can harm an unborn baby if the mother or the father is using vorinostat.

• If you are a woman, do not use vorinostat if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.

• If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.

• Tell your doctor right away if a pregnancy occurs while either the mother or the father is using vorinostat.

Do not breast-feed while using this medicine, and for at least 1 week after your last dose.

How should I take vorinostat?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take with food. Drink at least 2 liters of water each day to keep from getting dehydrated.

Swallow the capsule whole and do not chew, break, or open it. The medicine inside the capsule can be dangerous if it gets in your eyes or on your skin. If this happens, wash your skin with soap and water or rinse your eyes with water, and then call your doctor.

Tell your doctor if you have trouble swallowing the capsule whole.

Your blood sugar will need to be checked often, and you may need other blood tests.

Call your doctor if you are sick with vomiting or diarrhea, especially if you are diabetic and can...