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Vtama
  • Treatments
  • Plaque Psoriasis

Vtama

Generic name: tapinarof
Dosage form: cream, for topical use

Medically reviewed by Judith Stewart, BPharm. Last updated on May 25, 2022.

What is Vtama cream?

Vtama cream is a prescription medicine used on the skin (topical) to treat plaque psoriasis in adults.

It works by activating the aryl hydrocarbon receptors (AhR) in the skin to reduce inflammation. The way it works is similar to topical coal tar, which has been used in the treatment of psoriasis for more than a century.

What is Vtama cream used to treat?

Vtama is used to treat mild, moderate, and severe psoriasis in adults.

It can be used on all areas of the body, including on sensitive locations, such as the face, skin folds, and neck.

It is not known if the cream is safe and effective in children with psoriasis under 18 years of age.

Important information

Vtama cream is for use on the skin (topical use) only. Do not use the cream in your eyes, mouth, or vagina.

Before using Vtama cream

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

  • are pregnant or plan to become pregnant. It is not known if Vtama cream will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Vtama cream passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment.

What other drugs will affect Vtama cream?

Medicine used on the skin is not likely to be affected by other drugs you use.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use Vtama cream?

  • Use the cream exactly as your healthcare provider tells you to use it.
  • Apply a thin layer of the cream only to your psoriasis skin lesions one time each day. Avoid applying the cream to unaffected areas of your skin.
  • Wash your hands after applying the cream unless you are using it to treat your hands.
  • If someone else applies the cream for you, they should wash their hands after application.

Dosing information

Usual Adult Dosage for Plaque Psoriasis

- apply a thin layer of cream to affected areas once daily

- Use: topical treatment of plaque psoriasis in adults

Vtama side effects

The most common side effects include:

  • red raised bumps around the hair pores (folliculitis)
  • pain or swelling in the nose and throat (...