Vyndaqel

Generic name:tafamidis [ ta-FAM-id-is ]
Brand names: Vyndamax, Vyndaqel
Drug class:Transthyretin stabilizers

Medically reviewed by Drugs.com on Aug 27, 2021. Written by Cerner Multum.

What is Vyndaqel?

Vyndaqel affects a protein called transthyretin (TTR, made primarily in the liver). Transthyretin-mediated amyloidosis (ATTR) is a condition in which abnormal deposits of TTR protein build-up in many parts of the body, interfering with normal function. A build-up of TTR in the heart can lead to heart failure.

People with hereditary ATTR amyloidosis have a DNA mutation that can be passed from one generation to the next. People with wild-type ATTR amyloidosis do not have abnormal DNA and cannot pass on the condition.

Vyndaqel is used in adults with hereditary or wild type ATTR to treat cardiomyopathy (damage of the heart muscle) caused by a build-up of TTR.

Vyndaqel may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Tell your doctor if you have ever had:

• liver disease.

Your name may be listed on a Transthyretin Amyloidosis Outcome Survey registry to track the effects of tafamidis on your condition.

Vyndaqel may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor i...