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Vytorin
  • Treatments
  • High Cholesterol

Vytorin

Generic name:ezetimibe and simvastatinez-ET-i-mibe-and-SIM-va-stat-in ]
Drug class:Antihyperlipidemic combinations

Medically reviewed by Philip Thornton, DipPharm. Last updated on Nov 3, 2020.

What is Vytorin?

Vytorin contains a combination of ezetimibe and simvastatin. Ezetimibe reduces the amount of cholesterol absorbed by the body.

Simvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Vytorin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides, to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Vytorin is used together with a low-fat diet and other treatments to lower total cholesterol in adults and children who are at least 10 years old. It is not known whether this medicine reduces your risk of heart disease.

Warnings

You should not use Vytorin if you have active liver disease or abnormal liver function tests.

Do not use Vytorin if you are pregnant or if you could become pregnant. Use effective birth control.

Do not breastfeed while using ezetimibe and simvastatin.

The following drugs should not be used while you are taking Vytorin: boceprevir, cyclosporine, danazol, gemfibrozil, nefazodone, telaprevir, certain antibiotics (clarithromycin, erythromycin, telithromycin), antifungal medication (itraconazole, ketoconazole, posaconazole, voriconazole), or certain HIV/AIDS medication (atazanavir, cobicistat (Stribild, Tybost), indinavir, nelfinavir, r...