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Xigduo XR
  • Treatments
  • Diabetes
  • Type 2

Xigduo XR

Generic name:dapagliflozin and metforminDAP-a-gli-FLOE-zin-and-met-FOR-min ]
Drug class:Antidiabetic combinations

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jun 7, 2022.

What is Xigduo XR?

Xigduo XR extended release tablets contain a combination of dapagliflozin and metformin. Dapagliflozin and metformin are oral diabetes medicines that help control blood sugar levels. Dapagliflozin works by helping the kidneys get rid of glucose from your bloodstream. Metformin lowers glucose production in the liver and also causes your intestines to absorb less glucose.

Xigduo XR is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Xigduo XR is not for treating type 1 diabetes.

Xigduo XR is also used to lower the risk of needing to be in the hospital for heart failure in adults with type 2 diabetes who also have heart disease.

Xigduo XR is also used to reduce the risk of worsening kidney disease and death due to heart problems, and the need to be in the hospital for heart failure in adults with type 2 diabetes who also have chronic kidney disease.

Warnings

You should not use Xigduo XR if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Xigduo XR.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, troubl...