Xtandi

Generic name:enzalutamide [ ENZ-a-LOOT-a-mide ]
Drug classes:Antiandrogens, Hormones / antineoplastics

Medically reviewed by Philip Thornton, DipPharm. Last updated on Mar 2, 2022.

What is Xtandi?

Xtandi is an anti-androgen. It works in the body by preventing the actions of androgens (male hormones).

Xtandi is used to treat prostate cancer

Xtandi is sometimes used when the cancer no longer responds to treatment, but has not spread to other parts of the body.

Xtandi is also used when the cancer has responded to treatment and has spread to other parts of the body (metastatic).

Warnings

Although not for use by women, Xtandi can cause birth defects if the mother or the father is taking this medicine. Use a condom and one other form of birth control to prevent pregnancy during your treatment, and for at least 3 months after your treatment ends.

Xtandi may cause side effects on your spinal cord. Stop taking this medicine and call your doctor at once if you have severe low back pain, trouble walking or standing up, pain or weakness in your lower body, severe and worsening numbness or tingling, or sudden loss of bladder or bowel control.

Before taking this medicine

You should not use Xtandi if you are allergic to enzalutamide.

To make sure Xtandi is safe for you, tell your doctor if you have ever had:

• a seizure;

• a head injury, stroke, or brain tumor;

• heart disease, circulation problems;

• high blood pressure;

• diabetes; or

• high cholesterol or triglycerides (a type of fat in the blood).

Although not for use by women, Xtandi can cause birth defects if the mother or the father is taking this medicine. Do not use this medicine if you are pre...