Xuriden (Oral)

Generic name:uridine triacetate (oral route) [ URE-i-deen-trye-AS-e-tate ]
Drug classes:Antidotes, Miscellaneous metabolic agents

Medically reviewed by Drugs.com. Last updated on Jun 14, 2022.

Commonly used brand name(s)

In the U.S.

• Vistogard
• Xuriden

Available Dosage Forms:

• Granule

Therapeutic Class: Antidote

Uses for Xuriden

Uridine triacetate is used to treat hereditary orotic aciduria. Hereditary orotic aciduria is a rare metabolic disease that is caused by uridine deficiency. Uridine triacetate is a pyrimidine analog that works by replacing the uridine that cannot be normally produced in patients with hereditary orotic aciduria.

Uridine triacetate is also used as an emergency treatment for patients who had an overdose of the cancer medicines fluorouracil or capecitabine, or who develop certain severe or life-threatening side effects within 4 days of receiving these cancer medicines.

This medicine is available only with your doctor's prescription.

Before using Xuriden

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of uridine triacetate in children.

Geriatric

Although appropriate studies on the relationship of age to the effects of Vistogard® have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of Vistogard® in the elderly.

No information is available on the relationship of age to the effects of Xuriden™ in geriatric patients.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or toba...