Generic name:ziv-aflibercept [ ZIV-a-FLIB-er-sept ]
Drug class:VEGF/VEGFR inhibitors
What is Zaltrap?
Zaltrap is made from a human antibody fragment. It works by keeping new blood vessels from forming in a fast-growing tumor.
Zaltrap is used in combination with other medications to treat colorectal cancer that has spread to other parts of the body (metastatic).
Zaltrap is usually given after other medications did not work or have stopped working.
Warnings
You should not use Zaltrap if you have severe bleeding or uncontrolled hypertension (high blood pressure).
Before you receive Zaltrap, tell your doctor if you have high blood pressure, open sores or skin wounds, or if you have had surgery or dental work within the past 4 weeks.
If you need surgery, tell the surgeon ahead of time that you are using this medicine.
Zaltrap may cause serious and sometimes fatal bleeding. Call your doctor at once if you have any signs of unusual bleeding, including easy bruising, bloody stools, coughing up blood, or feeling light-headed or short of breath.
If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using Zaltrap. You may need to stop using the medicine at least 4 weeks before your surgery.
Before taking this medicine
To make sure Zaltrap is safe for you, tell your doctor if you have:
bleeding problems;
heart problems, high blood pressure;
open sores or skin wounds; or
surgery or dental work within the past 4 weeks.
Ziv-aflibercept may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective
