Zegerid OTC

Generic name:omeprazole and sodium bicarbonate [ oh-ME-pray-zol-and-SO-dee-um-by-KAR-bon-ate ]
Drug class:Proton pump inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jan 3, 2022.

What is Zegerid OTC?

Zegerid OTC contains a combination of omeprazole and sodium bicarbonate. Omeprazole is a proton pump inhibitor that decreases the amount of acid your stomach produces. Sodium bicarbonate is an antacid that raises the pH in your stomach to keep the omeprazole from breaking down in stomach acid.

Zegerid OTC is used to treat frequent heartburn that occurs on 2 or more days a week. It not intended for the immediate relief of heartburn.

It may take 1 to 4 days for Zegerid OTC to have full effect.

Warnings

The omeprazole in Zegerid OTC can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.

Omeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.

You may be more likely to have a broken bone while taking this medicine long term or more than once per day.

This medicine contains sodium bicarbonate, a form of salt. Tell your doctor if you have Bartter's syndrome (a rare kidney disorder), or if you are on a low-salt diet.

Before taking this medicine

You should not take Zegerid OTC if you are allergic to omeprazole or sodium bicarbonate, or if you are also taking any medication that contains rilpivirine (Edurant, Juluca, Complera, Odefsey).

Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

Zegerid OTC contains sodium bicarbonate, a form of salt. Each capsule contains the equivalent of 303 mg of sodium. If you are on a low-salt diet, you may not be able to use Zegerid OTC. Talk with your doctor.

To make sure Zegerid OTC is safe for you, tell your doctor or pharmacist if you have::

• a rare kidney disorder called Bartter's syndrome;

• liver disease;

• any allergies;

• heart failure;

• problems with acid-base (pH) balance in your body;

• low levels of calcium, magnesium, or potassium levels in your blood;

• if you are of Asian descent.

You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones hea...