Zencia Wash
Generic name:sulfacetamide sodium and sulfur
Dosage form: lotion
Drug class:Topical antibiotics
Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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(sodium sulfacetamide 9% & sulfur 4%)
In a vehicle containing Green Tea & Aloe
The Zencia Wash brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Zencia Wash Description
Sodium sulfacetamide is a sulfonamide with antibacterial activity while sulfur acts as a keratolyic agent. Chemically sodium sulfacetamide is N-[(4-aminophenyl) sulfonyl]- acetamide, monosodium salt monohydrate. The structural formula is:
Each mL of ZENCIA™WASH contains 90 mg of Sodium Sulfacetamide and 40 mg of Sulfur in a formulation consisting of: Aloe, Butylated Hydroxytoluene, Cetyl Alcohol, Disodium Oleamido MEA Sulfosuccinate, Edetate Disodium, Fragrance, Glyceryl Stearate and PEG 100 Stearate, Green Tea, Magnesium Aluminum Silicate, Methyl Paraben, Propyl Paraben, Purified Water, Sodium Cocoyl Isethionate, Sodium Methyl Cocoyl Taurate, Sodium Thiosulfate, Stearyl Alcohol and Xanthan Gum.
Zencia Wash - Clinical Pharmacology
The most widely accepted mechanism of action of sulfonamides is the Woods-Fildes theory, which is based on the fact that sulfonamides act as competitive antagonists to para-aminobenzoic acid (PABA), an essential component for bacterial growth. While absorption through intact skin has not been determined, sodium sulfacetamide is readily absorbed from the gastrointestinal tract when taken orally and excreted in the urine, largely unchanged. The biological half-life has variously been reported as 7 to 12.8 hours. The exact mode of action of sulfur in the treatment of acne is unknown, but it has been reported that it inhibits the growth of Propionibacte...
