Zirabev
Generic name:bevacizumab [ bev-a-CIZ-oo-mab ]
Brand names: Avastin, Mvasi, Zirabev
Drug class:VEGF/VEGFR inhibitors
What is Zirabev?
Zirabev is used to treat a certain type of brain tumor, and certain types of cancers of the kidney, liver, lung, colon, rectum, cervix, ovary, or fallopian tube. This medicine is also used to treat cancer of the membrane lining the internal organs in your abdomen. It is usually given as part of a combination of cancer medicines.
Zirabev may also be used for purposes not listed in this medication guide.
Warnings
Zirabev can make it easier for you to bleed. Seek emergency medical attention if you have any bleeding that will not stop. You may also have bleeding on the inside of your body.
Call your doctor if you have: signs of bleeding in your digestive tract--feeling very weak or dizzy, severe stomach pain, black or bloody stools, coughing up blood or vomit that looks like coffee grounds; or signs of bleeding in the brain--sudden numbness or weakness, slurred speech, severe headache, problems with vision or balance.
Do not use Zirabev within 28 days before or after a planned surgery.
Before taking this medicine
You may not be able to use use Zirabev if you are allergic to it, or:
if you have slow healing of a skin wound or surgical incision;
if you have had surgery within the past 4 weeks (28 days);
if you have recently been coughing up blood; or
if you plan to have surgery within the next 4 weeks (28 days).
Tell your doctor if you have ever had:
heart disease, high blood pressure;
a heart attack, stroke, or blood clots;
a bleeding or blood-clotting disorder; or
stomach or intestinal bleeding, or perforation (a hole or tear) in your esophagus, stomach, or intestines.
Zirabev may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose. Tell your doctor if you become pregnant.
Zirabev may cause a woman's ovaries to stop working correctly. Symptoms of ovarian failure include 3 or more missed menstrual periods in a row. This may affect your fertility (ability to have children). Talk to your doctor about your specific risks.
Do not breastfeed while using this me...
