Zovirax Cream

Generic name:acyclovir
Dosage form: cream
Drug class:Topical antivirals

Medically reviewed by Drugs.com. Last updated on Feb 1, 2021.

Indications and Usage for Zovirax Cream

Zovirax Cream is a herpes simplex virus (HSV) deoxynucleoside analogue DNA polymerase inhibitor indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents 12 years of age and older.

Zovirax Cream Dosage and Administration

Zovirax Cream should be applied 5 times per day for 4 days. Therapy should be initiated as early as possible following the onset of signs or symptoms of herpes labialis, i.e. during the prodrome or when lesions appear.

For adolescents 12 years of age and older, the dosage is the same as in adults.

Dosage Forms and Strengths

Each gram of Zovirax Cream contains 50 mg (equivalent to 5% w/w) of acyclovir.

Contraindications

Zovirax Cream is contraindicated in patients with known hypersensitivity to acyclovir, valacyclovir, or any component of the formulation.

Warnings and Precautions

General

Zovirax Cream should only be applied on the affected external aspects of the lips and face in patients with herpes labialis. Because no data are available, application to human mucous membranes is not recommended. Zovirax Cream is intended for cutaneous use only and should not be used in the eye or inside the mouth or nose.

Contact Sensitization

Zovirax Cream has a potential for irritation and contact sensitization [see Adverse Reactions (6.1)].

The effect of Zovirax Cream has not been established in immunocompromised patients.

Adverse Reactions

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction ra...