Generic name:brexanolone [ brex-AN-oh-lone ]
Drug class:Miscellaneous antidepressants
What is Zulresso?
Zulresso is a prescription medicine used to treat postpartum depression.
Zulresso is available only under a special program because it can cause excessive drowsiness or sudden loss of consciousness. You must be registered in the program and understand the risks and benefits of this medicine.
Zulresso is given as a continuous intravenous infusion over a total of 60 houts.
Warnings
Zulresso is given in a hospital or clinic setting where you can be watched closely for side effects.
Brexanolone can make you very drowsy, and may cause you to pass out. Tell your caregivers if you feel light-headed or feel like you cannot stay awake.
Before taking this medicine
Zulresso is not approved for use by anyone younger than 18 years old.
To make sure Zulresso is safe for you, tell your doctor if you have ever had:
kidney disease; or
if you drink large amounts of alcohol.
Some young people have thoughts about suicide while using an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Brexanolone may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of brexanolone on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
How is Zulresso given?
Zulresso is given as an infusion into a vein. A healthcare provider will give you this injection in a hospital or clinic setting.
