Generic name:ondansetron (oral) [ on-DAN-se-tron ]
Brand names: Zofran, Zofran ODT, Zuplenz
Drug class:5HT3 receptor antagonists
Medically reviewed by Drugs.com. Last updated on Oct 25, 2021.
What is Zuplenz?
Zuplenz blocks the actions of chemicals in the body that can trigger nausea and vomiting.
Zuplenz is used to prevent nausea and vomiting that may be caused by surgery, cancer chemotherapy, or radiation treatment.
Zuplenz may be used for purposes not listed in this medication guide.
Warnings
You should not use Zuplenz if you are also using apomorphine (Apokyn).
You should not use Zuplenz if you are allergic to ondansetron or to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi).
Serious side effects of Zuplenz include blurred vision or temporary vision loss (lasting from only a few minutes to several hours), slow heart rate, trouble breathing, anxiety, agitation, shivering, feeling like you might pass out, and urinating less than usual or not at all. Stop taking Zuplenz and call your doctor at once if you have any of these side effects. Ondansetron may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Before taking this medicine
You should not use Zuplenz if:
you are also using apomorphine (Apokyn); or
you are allergic to ondansetron or similar medicines (dolasetron, granisetron, palonosetron).
To make sure Zuplenz is safe for you, tell your doctor if you have:
liver disease;
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
congestive heart failure, slow heartbeats;
a personal or family history of long QT syndrome; or
a ...
