Zurampic

Generic name:lesinurad [ le-SIN-ure-ad ]
Drug class:Antihyperuricemic agents

Medically reviewed by Drugs.com. Last updated on Sep 13, 2021.

What is Zurampic?

Zurampic helps the kidneys remove uric acid from the body. Lesinurad is used together with other medicines that can cause the body to produce less uric acid.

Zurampic is used as part of a combination of medicines to treat high levels of uric acid in your blood, also called hyperuricemia. High levels of uric acid can lead to a condition called gout.

Zurampic should be used together with allopurinol (Zyloprim) or febuxostat (Uloric). It should not be used alone.

Warnings

You should not use Zurampic if you have severe kidney problems, or if you are on dialysis or have received a kidney transplant.

Zurampic can cause kidney failure, especially if you take it without your other prescribed medications. Call your doctor right away if you urinate less than usual or not at all, or if you have swelling in your feet or ankles, or shortness of breath.

Before taking this medicine

You should not use Zurampic if you are allergic to lesinurad, or if:

• you have severe kidney disease;

• you are on dialysis;

• you received a kidney transplant;

• you have Lesch-Nyhan syndrome (a genetic condition that increases uric acid levels in the blood); or

• you have tumor lysis syndrome (rapid breakdown of cancer cells).

To make sure Zurampic is safe for you, tell your doctor if you have:

• kidney disease;

• liver disease;

• heart disease; or

• a stomach disorder called gastroesophageal reflux disease (GERD).

It is not known whether Zurampic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Zurampic can make birth control pills less effective. Ask your doctor about using a non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

Other forms of hormonal contraception (injections, implants, skin patches, vaginal rings, and certain intrauterine devices) may not be effective enough to prevent pregnancy during your treatment with Zurampic.

It is not known whether lesinurad passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Zurampic is not approved for use by anyone younger than 18 years old.

How should I take Zurampic?

Take Zurampic exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Zurampic should be given in combination with other uric acid medication and it should not be used alone. Lesinurad is more likely to cause kidney failure if you take this medicine without your other prescribed medication.

Zurampic ...