Zyflo
Generic name:zileuton [ zye-LOO-ton ]
Drug class:Leukotriene modifiers
What is Zyflo?
Zyflo is used to prevent asthma attacks and for long-term management of asthma in adults and children at least 12 years old.
Zyflo may also be used for purposes not listed in this medication guide.
Warnings
Zyflo is not a fast-acting rescue medicine for asthma attacks. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working.
Call your doctor right away if you have any changes in behavior or sleep problems.
Before taking this medicine
You should not use Zyflo if you are allergic to it, or if you have:
liver disease; or
very high liver enzymes on a blood test.
Tell your doctor if you have ever had:
liver problems, dark urine, or jaundice (yellow eyes or skin); or
if you drink large amounts of alcohol.
Tell your doctor if you are pregnant or breastfeeding.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of zileuton on the baby.
How should I take Zyflo?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Zyflo tablets are usually taken 4 times a day at the same times each day, with or without food. If you cannot swallow a tablet whole, split it in half and take one half at a time.
Zyflo extended-release tablets are usually taken twice daily, within 1 hour after your morning and evening meals.
Swallow the extended-release tablet whole and do not crush, chew, or break it.
Your symptoms may not improve for several days or a few weeks. Keep using Zyflo even after you have no symptoms (a sign that the medicine is working).
Zyflo is not a fast-acting rescue medicine for asthma attacks. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working.
Do not change your dose or stop using asthma medication without your doctor's advice.
You will need frequent blood tests to check your liver function.
Store at room temperature away from moisture, heat, and light.
