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Zynlonta
  • Treatments
  • Diffuse Large B-Cell Lymphoma

Zynlonta

Generic name:loncastuximab tesirine-lpyl
Dosage form:   lyophilized powder for injection, for intravenous use
Drug class:Miscellaneous antineoplastics

Medically reviewed by Judith Stewart, BPharm. Last updated on Sep 1, 2021.

What is Zynlonta?

Zynlonta is a prescription medicine used to treat adults with certain types of large B-cell lymphoma that has come back (relapsed) or that did not respond to previous treatment (refractory), who have already received two or more treatments for their cancer.

It is not known if this medicine is safe and effective in children.

Before receiving Zynlonta

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

  • have an active infection or have had one recently.
  • have liver problems.
  • are pregnant or plan to become pregnant. Zynlonta can harm your unborn baby.
    Females who can become pregnant:
    • Your healthcare provider may do a pregnancy test before starting treatment.
    • You should use effective birth control (contraception) during treatment, and for 9 months after the last dose. Talk to your healthcare provider about effective birth control. Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment.

Males with female partners who can become pregnant:

    • You should use effective birth control (contraception) during treatment, and for 6 months after the last dose.
    • are breastfeeding or plan to breastfeed. It is not known if Zynlonta passes into breast milk. Do not breastfeed during treatment with Zynlonta and for 3 months after the last dose.

Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcar...