Zypram Cream

Generic name:hydrocortisone acetate and pramoxine hydrochloride
Dosage form: cream
Drug class:Anorectal preparations

Medically reviewed by Drugs.com. Last updated on Jun 21, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

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Zypram Cream Description

ZyPram™ Cream is a topical preparation containing hydrocortisone acetate 2.35% in a cream base and pramoxine hydrochloride 1% in a hydrophilic cream base1. Hydrocortisone acetate has a chemical name pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11,17-dihydroxy-(11β)-. It has the following structural formula:

Pramoxine hydrochloride has chemical name 4-[3-(4-butoxyphenoxy) propyl]morpholine hydrochloride, and has the following structure:

Active ingredients: Hydrocortisone Acetate 2.35% and Pramoxine Hydrochloride 1%.

Inactive ingredients: Ammonium Acryloyldimethyltaurate/VP-Copolymer, Benzyl Alcohol, Cetearyl Alcohol, Cetearyl Olivate (&) Sorbitan Olivate, PEG-12 Glyceryl Distearate=GDS-12, PEG-12 Glyceryl Dimyristate=GDM-12, Glycerine, Glyceryl Stearate, Methyl Paraben, PEG 100 Stearate, Polysorbate 60, Propylene Glycol, Purified Water, Sodium Lauryl Sulfate, White Petrolatum.

Cleansing Wipe (2.2 grams solution per wipe) Contains:

Citric Acid . . . . . . . . . . . . . . . . . . . . . . . 22 mg

Aloe Vera . . . . . . . . . . . . . . . . . . . . . . . 11 mg

Vitamin E (dl-tocopheryl acetate) . . . . . . 2.2 mg

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