10 Percent FreAmine III

Generic name: isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, alanine, arginine, histidine, proline, serine, glycine, cysteine, phosphoric acid and sodium bisulfite
Dosage form: injection, solution
Drug class:Intravenous nutritional products

Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.

10 Percent FreAmine III Description

10% FreAmine III (Amino Acid Injection) is a sterile, nonpyrogenic, hypertonic solution containing crystalline amino acids. Each 1000 mL provides a total of 15.3 g of nitrogen in 97 g of amino acids equal to 95.6 grams of protein equivalent. All amino acids designated USP are the "L"-isomer, with the exception of Glycine USP, which does not have an isomer.

Each 100 mL contains:

Essential amino acids

Isoleucine USP ..... 0.69 g

Leucine USP ..... 0.91 g

Lysine USP ..... 0.73 g

(added as Lysine Acetate USP ..... 1.02 g)

Methionine USP ..... 0.53 g

Phenylalanine USP ..... 0.56 g

Threonine USP ..... 0.40 g

Tryptophan USP ..... 0.15 g

Valine USP ..... 0.66 g

Nonessential amino acids

Alanine USP ..... 0.71 g

Arginine USP ..... 0.95 g

Histidine USP ..... 0.28 g

Proline USP ..... 1.12 g

Serine USP ..... 0.59 g

Glycine USP ..... 1.40 g

Cysteine ..... <0.016 g

(as Cysteine HCl•H2O USP ..... <0.024 g)

Phosphoric Acid NF..... 0.12 g

Sodium Bisulfite (as an antioxidant) ..... <0.10 g

Water for Injection USP ..... qs

pH adjusted with Glacial Acetic Acid USP
pH: 6.5 (6.0 – 7.0)
Calculated Osmolarity: 950 mOsmol/liter

Concentration of Electrolytes (mEq/liter): Sodium 10
Phosphate (HPO) 20 (10 mmole P/liter); Acetate Approx. 89
(provided as acetic acid and lysine acetate); Chloride <3.