Beleodaq
Generic name:belinostat [ be-LIN-oh-stat ]
Drug class:Histone deacetylase inhibitors
What is Beleodaq?
Beleodaq is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Beleodaq injection is used to treat peripheral T-cell lymphoma after other cancer treatments did not work or have stopped working.
Beleodaq was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, non-small cell lung tumors responded to this medicine. However, it has not been shown that belinostat can improve symptoms or lengthen survival time.
Warnings
Beleodaq affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, cough, flu-like symptoms, or unusual bleeding or bruising.
Belinostat can harm your unborn baby. You should not become pregnant while receiving Beleodaq. Tell your doctor right away if you become pregnant while receiving this medicine.
Before taking this medicine
To make sure Beleodaq is safe for you, tell your doctor if you have ever had:
an infection;
high-dose or intensive chemotherapy;
liver or kidney disease; or
Belinostat can harm an unborn baby if the mother or the father is using this medicine.
If you are a woman, do not use Beleodaq if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Beleodaq.
Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.
How is Beleodaq given?
Beleodaq injection is given as an infusion into a vein. A healthcare provider will give you this injection.
This medicine must be given slowly, and the infusion can take at least 30 minutes to complete.
Beleodaq is given in a 21-day treatment cycle. You may need to use the medicine only during the first 5 days of each cycle. Your doctor will determine how long to treat you with this medicine.
You may be given medication to prevent nausea, vomiting, or diarrhea while you are receiving Beleodaq.
Belinostat affects your immune system. You may...
