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Belumosudil
  • Treatments
  • Graft-versus-host disease

Belumosudil

Generic name: belumosudil [ BEL-ue-MOE-soo-dil ]
Brand name: Rezurock
Dosage form: oral tablet (200 mg)
Drug class:Selective immunosuppressants

Medically reviewed by Drugs.com on Mar 3, 2022. Written by Cerner Multum.

What is belumosudil?

Belumosudil is used to treat chronic graft-versus-host disease after other at least two other treatments did not work.

Belumosudil is for use in adults and children at least 12 years old.

Belumosudil may also be used for purposes not listed in this medication guide.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

Tell your doctor if you have ever had liver or kidney problems.

You may need to have a negative pregnancy test before starting this treatment.

Both men and women using belumosudil should use effective birth control to prevent pregnancy. Belumosudil can harm an unborn baby if the mother or father is using this medicine.

Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs.

Pregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.

Do not breastfeed while using this medicine, and for at least 1 week after your last dose.

How should I take belumosudil?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Belumosudil is usually taken once per day with a meal. Follow your doctor's dosing instructions very carefully.

Take with a full glass of water, at the same time each day.

Swallow the tablet whole and do not crush, chew, or break it.

You will need frequent blood tests to check your liver function.

Store tightly closed at room temperature, away from moisture and heat.

Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.

What happens if I miss a dose?

Take the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once-daily schedule. Do not take two doses in one day.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking belumosudil?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Belumosudil side effects

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