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Bempedoic acid and ezetimibe
  • Treatments
  • High Cholesterol
  • Familial Heterozygous

Bempedoic acid and ezetimibe

Generic name: bempedoic acid and ezetimibe [ BEM-pe-DOE-ik-AS-id-and-e-ZET-i-mibe ]
Brand name: Nexlizet
Dosage form: oral tablet (180 mg-10 mg)
Drug class:Antihyperlipidemic combinations

Medically reviewed by Drugs.com on Aug 4, 2020. Written by Cerner Multum.

What is bempedoic acid and ezetimibe?

Bempedoic acid and ezetimibe is a combination medicine that is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL).

Bempedoic acid and ezetimibe is used together with a low-fat diet and other medicines to lower LDL cholesterol in adults with an inherited form of high cholesterol. bempedoic acid and ezetimibe is also used in adults with heart disease who need additional lowering of LDL cholesterol.

It is not known whether this medicine reduces your risk of heart attack, stroke, or death.

Bempedoic acid and ezetimibe may also be used for purposes not listed in this medication guide.

Warnings

Some cholesterol medications should not be taken at the same time. If you take ezetimibe with another cholesterol medicine, follow your doctor's dosing instructions very carefully.

Before taking this medicine

You should not use bempedoic acid and ezetimibe if you are allergic to bempedoic acid or ezetimibe.

You may not be able to use bempedoic acid and ezetimibe if you have severe liver or kidney disease, or if you are on dialysis.

This medicine may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the arm, shoulder, or Achilles' tendon of the heel. This can happen during treatment or several weeks after you start taking bempedoic acid and ezetimibe. Tendon problems may be more likely if you are older than 60, if you have kidney failure, if you already have tendon problems, or if you use steroid medicine or certain antibiotics (such as Cipro or Levaquin).

Tell your doctor if you have ever had:

It is not known whether this medicine will harm an unborn baby. Tell your doctor right away if you become pregnant.

You should not breastfeed while using this medicine.

Bempedoic acid and ezetimibe is not approved for use by anyone younger than 18 years old.

How should I take bempedoic acid and ezetimibe?

Follow all directions on your prescri...