Acrivastine and pseudoephedrine

Generic name: acrivastine and pseudoephedrine [ a-KRIV-a-steen-and-SOO-doe-ee-FED-rin ]
Brand name: Semprex-D
Dosage form: oral capsule (8 mg-60 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Dec 10, 2021. Written by Cerner Multum.

What is acrivastine and pseudoephedrine?

Acrivastine and pseudoephedrine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies.

Acrivastine and pseudoephedrine may also be used for purposes not listed in this medication guide.

Warnings

You should not use acrivastine and pseudoephedrine if you have severe or uncontrolled high blood pressure or coronary artery disease.

Do not use acrivastine and pseudoephedrine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Before taking this medicine

You should not use this medicine if you are allergic to acrivastine or pseudoephedrine, or if:

• you have severe or uncontrolled high blood pressure;

• you have severe coronary artery disease (hardened arteries);

• you are allergic to other antihistamines such as triprolidine; or

• you are allergic to other decongestants such as phenylephrine or phenylpropanolamine.

Do not use acrivastine and pseudoephedrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have ever had:

• heart disease or high blood pressure;

• diabetes;

• glaucoma;

• an ulcer or obstruction in the stomach;

• a thyroid disorder;

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