Berinert
Generic name:complement C1 esterase inhibitor [ KOM-ple-ment-C1 ES-ter-ase-in-HIB-it-or ]
Drug class:Hereditary angioedema agents
What is Berinert?
Berinert is a man-made form of a protein that occurs naturally in the blood stream and helps control swelling in the body. People with a condition called hereditary angioedema do not have enough of this protein. Hereditary angioedema can cause attacks of swelling and symptoms such as stomach problems or trouble breathing.
Berinert is used in people with hereditary angioedema.
Berinert is used to treat attacks of angioedema. The Cinryze and Haegarda brands are used to prevent attacks of angioedema.
Warnings
You should not use Berinert if have ever had a life-threatening allergic reaction to complement C1 esterase inhibitor.
Before you receive Berinert, tell your doctor if you have a history of stroke or blood clot.
Stop the Berinert infusion and get emergency medical help if you have any of these signs of an allergic reaction: hives; wheezing or difficult breathing; feeling like you might pass out; or swelling of your face, lips, tongue, or throat.
Other serious side effects may include sudden numbness or weakness, chest pain, confusion, pain or swelling, and problems with vision, speech, or balance.
Berinert is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medicine.
Before taking this medicine
You should not use Berinert if have ever had a life-threatening allergic reaction to complement C1 esterase inhibitor.
Tell your doctor if you have ever had:
a stroke or blood clot;
heart problems; or
an "in-dwelling" catheter.
Tell your doctor if you are pregnant or breast-feeding.
Berinert is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.
How should I use Berinert?
Use Berinert exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Berinert is injected into a vein through an IV.
You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or...
